中文名稱:兔抗SMG7多克隆抗體
英文名稱: Anti-SMG7 rabbit polyclonal antibody
別 名: EST1C; SGA56M; C1orf16
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃) 避光
抗 原: SMG7
宿 主: Rabbit
反應(yīng)種屬: Human
標(biāo) 記 物: Unconjugate
克隆類型: Unconjugate
技術(shù)規(guī)格
Background: |
This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Applications: |
WB, IF |
Name of antibody: |
SMG7 |
Immunogen: |
Synthesized peptide derived from internal of human SMG7. |
Full name: |
SMG7 nonsense mediated mRNA decay factor |
Synonyms: |
EST1C; SGA56M; C1orf16 |
SwissProt: |
Q92540 |
WB Predicted band size: |
127 kDa |
WB Positive control: |
Hela cells, Jurkat cells, 293 cells and Huvec cells lysates |
WB Recommended dilution: |
500-3000 |
IF positive control: |
HepG2 cells |
IF Recommend dilution: |
100-500 |