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  • 產(chǎn)品名稱:兔抗SMG7多克隆抗體

  • 產(chǎn)品型號:100ul
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詳情介紹:

中文名稱:兔抗SMG7多克隆抗體 

英文名稱: Anti-SMG7 rabbit polyclonal antibody

別      名: EST1C; SGA56M; C1orf16

相關(guān)類別: 一抗

儲      存: 冷凍(-20℃) 避光

抗      原: SMG7

宿      主: Rabbit

反應(yīng)種屬: Human

標(biāo) 記 物: Unconjugate

克隆類型: Unconjugate

技術(shù)規(guī)格

Background:

This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Applications:

WB, IF

Name of antibody:

SMG7

Immunogen:

Synthesized peptide derived from internal of human SMG7.

Full name:

SMG7 nonsense mediated mRNA decay factor

Synonyms:

EST1C; SGA56M; C1orf16

SwissProt:

Q92540

WB Predicted band size:

127 kDa

WB Positive control:

Hela cells, Jurkat cells, 293 cells and Huvec cells lysates

WB Recommended dilution:

500-3000

IF positive control:

HepG2 cells

IF Recommend dilution:

100-500


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